RNA is synthesized 5′ –> 3′ (same direction as DNA synthesis) RNA polymerase reads the template strand of DNA 3′ –> 5′.The enzyme RNA polymerase reads the template strand of DNA and synthesizes an RNA molecule whose bases are complementary to the template strand of DNA.Transcription is the process of using DNA as a template to make an RNA molecule: This video gives a highly simplified overview of the central dogma of molecular biology:Īnd this video provides an animated overview of gene expression in a eukaryotic cell: Although information can flow reversibly between DNA and RNA via transcription and reverse transcription, no mechanism has yet been found for alterations in protein amino acid sequence to somehow effect a corresponding change in the RNA or DNA. Information encoded in DNA is transcribed to RNA, and RNA is translated to a linear sequence of amino acids in protein. Compare and contrast prokaryotic and eukaryotic transcription and translationįrancis Crick coined the phase “the Central Dogma” to describe the flow of information from nucleic acid to protein.Predict the likely effects of mutations in DNA on protein amino acid sequence, structure and function.
Describe the process of and key components required for translation.
#Gene expression transcription and translation code#
Use the genetic code to predict the protein amino acid sequence translated from an mRNA sequence.
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